Certificate of Analysis
| Product Name: | Pemetrexed Disodium Hydrate |
| Catalog Number: | M5866 |
| CAS Number: | 357166-30-4 |
Physical and Chemical Properties
| Formula: | C20H21N5O6.5/2H2O.2Na |
| Molecular Weight: | 516.42 |
| Solubility: | Water ≥ 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.67% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |