Certificate of Analysis
| Product Name: | PD-1/PD-L1-IN 3 TFA |
| Catalog Number: | M31044 |
Physical and Chemical Properties
| Formula: | C91H127F3N24O20S |
| Molecular Weight: | 1966.19 |
| Form: | Solid |
| Solubility: | Water 50 mg/mL (ultrasonic) |
| Storage: | Store at ≤ -20°C, protect from light, dry, sealed |
Product Information
| Description: | PD-1/PD-L1-IN 3 TFA, a macrocyclic peptide, is a potent and selective inhibitor of the PD-1/PD-L1 and CD80/PD-L1 interactions. PD-1/PD-L1-IN 3 TFA interferes with PD-L1 binding to PD-1 and CD80 by binding to PD-L1, with IC50s of 5.60 nM and 7.04 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |