Certificate of Analysis
| Product Name: | Palbociclib |
| Catalog Number: | M6167 |
| CAS Number: | 571190-30-2 |
Physical and Chemical Properties
| Formula: | C24H29N7O2 |
| Molecular Weight: | 447.53 |
| Solubility: | DMSO 10 mg/mL (Ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.67% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Palbociclib is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |