Certificate of Analysis
| Product Name: | NSC 66811 |
| Catalog Number: | M2207 |
| CAS Number: | 6964-62-1 |
Physical and Chemical Properties
| Formula: | C23H20N2O |
| Molecular Weight: | 340.42 |
| Solubility: | DMSO 40 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.00% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NSC 66811 is a potent MDM2 inhibitor with Ki value of 120 nM, which disrupts MDM2-p53 interaction and activates p53 function. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |