Certificate of Analysis
| Product Name: | NPS-2143 |
| Catalog Number: | M3486 |
| CAS Number: | 284035-33-2 |
Physical and Chemical Properties
| Formula: | C24H25ClN2O2 |
| Molecular Weight: | 408.92 |
| Solubility: | DMSO 80 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Product Information
| Description: | NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |