Certificate of Analysis
| Product Name: | NAPQI |
| Catalog Number: | M30204 |
| CAS Number: | 50700-49-7 |
Physical and Chemical Properties
| Formula: | C8H7NO2 |
| Molecular Weight: | 149.15 |
| Form: | Solid |
| Storage: | -80°C, protect from light, sealed |
| Chemical Structure: |  |
Product Information
| Description: | NAPQI is the toxic metabolite of Acetaminophen. NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |