Certificate of Analysis
| Product Name: | Leptomycin B |
| Catalog Number: | M6903 |
| CAS Number: | 87081-35-4 |
Physical and Chemical Properties
| Formula: | C33H48O6 |
| Molecular Weight: | 540.74 |
| Form: | Melting point 41-44°C |
| Solubility: | DMSO 90 mg/mL |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Product Information
| Description: | Leptomycin B (CI 940; LMB (LMB) is a protein exit nuclear transport inhibitor. Leptomycin deactivates CRM1/exportin 1 by covalent modification at cysteine residues. Leptomycin B is a potent antifungal antibiotic that blocks the eukaryotic cell cycle. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |