Certificate of Analysis
| Product Name: | Larazotide acetate |
| Catalog Number: | M10370 |
| CAS Number: | 881851-50-9 |
Physical and Chemical Properties
| Formula: | C34H59N9O12 |
| Molecular Weight: | 785.89 |
| Solubility: | Water 15 mg/mL; DMSO 2 mg/mL |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Larazotide acetate also known as AT-1001, is a tight junction regulator and reverses leaky junctions to their normally closed state. Larazotide acetate is a peptide which is an orally active zonulin antagonist. Larazotide acetate shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |