Certificate of Analysis
| Product Name: | Lapatinib ditosylate |
| Catalog Number: | M14137 |
| CAS Number: | 388082-77-7 |
Physical and Chemical Properties
| Formula: | C43H42ClFN4O10S3 |
| Molecular Weight: | 925.46 |
| Solubility: | DMSO 100 mg/mL |
| Storage: | 2-8°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Product Information
| Description: | Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |