Certificate of Analysis
| Product Name: | Lapaquistat acetate |
| Catalog Number: | M28996 |
| CAS Number: | 189060-13-7 |
Physical and Chemical Properties
| Formula: | C33H41ClN2O9 |
| Molecular Weight: | 645.14 |
| Form: | Solid |
| Solubility: | DMSO 50 mg/mL (ultrasonic) |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Product Information
| Description: | Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway. Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |