Certificate of Analysis
| Product Name: | L-Tyrosine 7-amido-4-methylcoumarin |
| Catalog Number: | M59168 |
| CAS Number: | 94099-57-7 |
Physical and Chemical Properties
| Formula: | C19H18N2O4 |
| Molecular Weight: | 338.36 |
| Form: | Powder |
| Solubility: | 80% acetic acid: 50 mg/mL, clear to slightly hazy, faintly yellow |
| Storage: | -20°C |
| Chemical Structure: |  |
Product Information
| Description: | L-Tyrosine 7-amido-4-methylcoumarin (H-Tyr-AMC) is a synthetic substrate that is used in the study of serine proteases. It is reversibly bound to Sephadex G-100 and is hydrolyzed by protease enzymes in an acidic environment, generating an AMC chromatographic peak. This product has been shown to inhibit serine protease activity and, when incubated with the enzyme, reduces the hydrolysis of synthetic substrates. Synthetic H-Tyr-AMC can be used to study the inhibition of serine proteases by various inhibitors and their binding sites on the enzyme. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |