Certificate of Analysis
| Product Name: | JTE-952 |
| Catalog Number: | M28057 |
| CAS Number: | 1255303-54-8 |
Physical and Chemical Properties
| Formula: | C30H34N2O6 |
| Molecular Weight: | 518.6 |
| Form: | Solid |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Product Information
| Description: | JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |