Certificate of Analysis
| Product Name: | Hydroxyfasudil hydrochloride |
| Catalog Number: | M5260 |
| CAS Number: | 155558-32-0 |
Physical and Chemical Properties
| Formula: | C14H17N3O3S·HCl |
| Molecular Weight: | 343.83 |
| Solubility: | DMSO: ≥ 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.82% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Hydroxyfasudil (HA-1100), an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |