Certificate of Analysis
| Product Name: | Olverembatinib dimesylate |
| Catalog Number: | M2749 |
| CAS Number: | 1421783-64-3 |
Physical and Chemical Properties
| Formula: | C29H27F3N6O.2CH4O3S |
| Molecular Weight: | 724.77 |
| Solubility: | DMSO 90 mg/mL; Water 40 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.30% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Olverembatinib (GZD824) dimesylate is a third-generation oral effective BCR-ABL inhibitor, acting on BCR-ABL (WT) and BCR-ABL (T315I) with IC50 of 0.34 nM and 0.68 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |