Certificate of Analysis
| Product Name: | GSK484 hydrochloride |
| Catalog Number: | M8603 |
| CAS Number: | 1652591-81-5 |
Physical and Chemical Properties
| Formula: | C27H31N5O3.HCl |
| Molecular Weight: | 510.03 |
| Solubility: | DMSO 100 mg/mL; Water 50 mg/mL |
| Storage: | 2-8°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.37% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | GSK484 hydrochloride is a potent selective reversible inhibitor of protein arginine deiminase PAD4, an enzyme believed to play a role in granulocyte and macrophage development leading to inflammation and immune response, and overexpressed in many tumors. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |