Certificate of Analysis
| Product Name: | Gap19 TFA |
| Catalog Number: | M20821 |
| CAS Number: | 1507930-57-5 (free base) |
Physical and Chemical Properties
| Formula: | C57H97F3N14O15 |
| Molecular Weight: | 1275.46 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL; Water 100 mg/mL |
| Storage: | Store at ≤ -20°C, dry, sealed |
| Chemical Structure: |  |
Product Information
| Description: | Gap19 TFA is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. Gap19 TFA blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |