Certificate of Analysis
| Product Name: | FTY720 hydrochloride |
| Catalog Number: | M1712 |
| CAS Number: | 162359-56-0 |
Physical and Chemical Properties
| Formula: | C19H33NO2.HCl |
| Molecular Weight: | 343.9 |
| Solubility: | DMSO ≥ 60 mg/mL; Water 35 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.46% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Fingolimod (FTY720) HCl is a 1-phospho-neuraminol S1P receptor antagonist with an IC50 of 0.33 nM. , FTY720 can dephosphorylate AMPK by activating PP2A and reduce the expression level of phosphorylated eEF2K, ultimately leading to ADCD and iron death in human multiple myeloma cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |