Certificate of Analysis
| Product Name: | ERAS-4001 |
| Catalog Number: | M66241 |
| CAS Number: | 3024878-19-8 |
Physical and Chemical Properties
| Formula: | C36H39ClF4N8O3 |
| Molecular Weight: | 743.19 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Product Information
| Description: | ERAS-4001 is a pan-KRAS inhibitor, it has potent antitumor activities and significantly inhibits the proliferation of wild-type and mutant (such as KRASG12D, KRASG12V and KRASG12C) cancer cells. ERAS-4001 binds to both wild-type KRAS and the KRAS G12X mutant, and inhibits downstream signalling by KRAS via effector proteins such as the RAF protein family. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |