Certificate of Analysis
| Product Name: | Entrectinib |
| Catalog Number: | M5613 |
| CAS Number: | 1108743-60-7 |
Physical and Chemical Properties
| Formula: | C31H34F2N6O2 |
| Molecular Weight: | 560.64 |
| Solubility: | DMSO 90 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: | .gif) |
Analytical Data
| QC Standard: | 99.81% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Entrectinib (RXDX-101) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |