Certificate of Analysis
| Product Name: | Dooku1 |
| Catalog Number: | M10812 |
| CAS Number: | 2253744-54-4 |
Physical and Chemical Properties
| Formula: | C13H9Cl2N3OS |
| Molecular Weight: | 326.2 |
| Form: | Solid |
| Solubility: | DMSO 90 mg/mL |
| Storage: | -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.95% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+Incoming, IC50 values in HEK 293 cells and HUVECs are 1.3 μM and 1.5 μM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |