| Description: |
Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary. Diosimin is also an agonist of the aryl hydrocarbon receptor (AhR), capable of upregulating the expression of p53, caspase 3, and caspase 9 in A431 cells, while downregulating the levels of Bcl-2 and matrix metalloproteinases (MMP-2 and MMP-9). Its metabolite, diosmetin, inhibits 3H-dopamine uptake in a dose-dependent manner with an IC50 value of 4 μM. |
| Stability and Solubility Advice: |
Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |
