Certificate of Analysis
| Product Name: | CB-5083 |
| Catalog Number: | M13704 |
| CAS Number: | 1542705-92-9 |
Physical and Chemical Properties
| Formula: | C24H23N5O2 |
| Molecular Weight: | 413.47 |
| Solubility: | DMSO 90 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Product Information
| Description: | CB-5083 is a first-in-class, potent and selective, orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |