Certificate of Analysis

 

Product Name: BI-D1870
Catalog Number: M1948
CAS Number: 501437-28-1

Physical and Chemical Properties
Formula: C19H23F2N5O2
Molecular Weight: 391.42
Solubility: DMSO 80 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: BI-D1870 Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: BI-D1870 is an ATP-competitive, cell permeable and brain penetrated inhibitor of the p90 RSK (ribosomal S6 kinase) with IC50 values of 31 nM, 24 nM, 18 nM, 15 nM for RSK1, RSK2, RSK3, RSK4, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.