Certificate of Analysis
| Product Name: | Osimertinib mesylate (AZD-9291 mesylate) |
| Catalog Number: | M5099 |
| CAS Number: | 1421373-66-1 |
Physical and Chemical Properties
| Formula: | C29H37N7O5S |
| Molecular Weight: | 595.71 |
| Solubility: | DMSO 9 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: | -chemical-structure.gif) |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Osimertinib mesylate (AZD-9291 mesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |