Certificate of Analysis
| Product Name: | Apremilast |
| Catalog Number: | M2030 |
| CAS Number: | 608141-41-9 |
Physical and Chemical Properties
| Formula: | C22H24N2O7S |
| Molecular Weight: | 460.5 |
| Solubility: | DMSO 40 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.52% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Apremilast is a novel, orally available small molecule inhibitor of PDE4 with IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |