Certificate of Analysis
| Product Name: | AF 353 |
| Catalog Number: | M3949 |
| CAS Number: | 865305-30-2 |
Physical and Chemical Properties
| Formula: | C14H17IN4O2 |
| Molecular Weight: | 400.21 |
| Form: | Solid |
| Solubility: | DMSO 80 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.01% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | AF-353 is a novel, potent and orally bioavailable P2X3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |