Certificate of Analysis
| Product Name: | Acolbifene hydrochloride |
| Catalog Number: | M45336 |
| CAS Number: | 252555-01-4 |
Physical and Chemical Properties
| Formula: | C29H32ClNO4 |
| Molecular Weight: | 494.02 |
| Form: | Solid |
| Solubility: | DMSO >100 mg/mL |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Product Information
| Description: | Acolbifene hydrochloride is an active metabolite of EM800 and an orally available, selective estrogen receptor modulator (SERM) that inhibits estradiol-induced ERα (IC50 = 2 nM) and ERβ (IC50 = 0.4 nM) transcriptional activity, has significant anti-estrogenic effects on the mammary gland and uterus, and has anticancer activity. possesses anticancer activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |