| Cat.No. | Name | Information |
|---|---|---|
| M55043 | Cinpanemab | Cinpanemab (BIIB054) is a human-derived monoclonal antibody that binds to α-synuclein. Cinpanemab can be used for the research of Parkinson's disease. |
| M55042 | Cofetuzumab | Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7. |
| M55041 | Crizanlizumab | Crizanlizumab is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). Crizanlizumab prevents vaso-occlusive crises (VOCs). |
| M54716 | Trontinemab | Trontinemab is a bispecific human IgG1-κ antibody that targets amyloid β A4 precursor protein (APP) and transferrin receptor (TFRC).Trontinemab may be used in Alzheimer's disease-related studies. |
| M54553 | Erfonrilimab | Erfonrilimab is a humanized single-domain bispecific antibody-Fc fusion protein (VH-VH-h-CH2-CH3 dimer) targeting the immune checkpoints PD-L1 and CTLA-4. |
| M54551 | Rademikibart | Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Rα to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Rα epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Rα from other species. Rademikibart does not bind to IL-4Rα of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases. |
| M54547 | Enlonstobart | Enlonstobart is a recombinant humanized anti-PD-1 IgG4ҡ monoclonal antibody that can be used for tumor-related studies. |
| M50198 | Pelgifatamab | Pelgifatamab is a monoclonal antibody targeting prostate cancer-specific membrane antigen (PSMA) for prostate cancer-related studies. |
| M49947 | Ifabotuzumab | Ifabotuzumab is an IgG1κ antibody (KD=610 pM) targeting EphA3. Ifabotuzumab is able to cause apoptosis of tumor cells and activate antibody-dependent cell-mediated cytotoxicity (ADCC), which disrupts the tumor vascular system. In addition, Ifabotuzumab reduces idiopathic pulmonary fibrosis (IPF) CCR10+ cells and ameliorates pulmonary fibrosis. |
| M49822 | Tanruprubart | Tanruprubart (ANX005) is a monoclonal antibody that blocks the activation of the entire classical signaling pathway by inhibiting complement protein C1q, which is upstream of the complement cascade reaction, while also maintaining the functional integrity of other complement pathways. It can be used in studies related to Guillain-Barre Syndrome (GBS). |
| M49437 | Afimkibart | Afimkibart (PF-06480605) is an IgG1 human monoclonal antibody against TNF-like ligand 1A (TL1A, TNFSF15), which can be used in studies related to ulcerative colitis (UC). |
| M45360 | LYT-200 | Research Grade Anti-Human LGALS9 (LYT-200) is a monoclonal antibody that targets galectin-9 (galectin-9) and has antitumor activity. |
| M45266 | Linvoseltamab | Linvoseltamab is a bispecific antibody targeting BCMA (TNFRSF17) and CD3. Linvoseltamab is used in studies related to relapsed/refractory multiple myeloma (R/R MM). |
| M45249 | DCBY02 | DCBY02 is a monoclonal antibody targeting CD93 for studies related to solid tumors. |
| M45157 | OS2966 | OS2966 is a first-in-class (first-in-class) neutralizing anti-CD29 monoclonal antibody that selectively modulates CD29 (integrin b1 subunit) and can be used in glioblastoma-related studies. |
| M40939 | Rat IgG2b Isotype Control In vivo | Rat IgG2b Isotype Control In vivo monoclonal antibody (Clone:1-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications. |
| M40936 | Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo | Anti-Mouse CD4 (Clone GK1.5) antibody recognizes an epitope on Mouse CD4. |
| M40935 | Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo | Anti-Mouse IFNγ (interferon gamma) (Clone H22) antibody recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. |
| M40934 | Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo | Anti-Mouse CTLA-4 Antibody (Clone 9D9) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes. |
| M40918 | Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo | Anti-Mouse Ly6G antibody (Clone 1A8) In vivo recognizes an epitope on mouse Ly6G. Ly6G is expressed by neutrophils. |
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