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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M65735 Anti-Mouse IL-13 Antibody (Clone ID: BAK209B11) Anti-Mouse IL-13 Antibody is an anti-mouse IL-13 IgG2a monoclonal antibody.
M65712 Recombinant Anti-mouse PD-1 mAb (Clone RMP1-14) InVivo
M59290 Clivatuzumab Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers.
M59289 U3-1784 U3-1784 is a humanized antibody that targets FGFR4/CD334. U3-1784 is equipped with a huIgG1 heavy chain and a huλ light chain.
M59270 Coltuximab Coltuximab is a humanized antibody that targets CD19. Coltuximab is composed of huIgG1 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 145 kDa.
M59213 Etalanetug Etalanetug (E2814) is a humanized high-affinity IgG1 antibody that targets tau protein (MAPT) and can cross the blood-brain barrier. Etalanetug inhibits the spread of pathological tau protein through high-affinity binding to the microtubule-binding region (MTBR).
M59211 Peresolimab Peresolimab is a humanized IgG1-κ antibody targeting to PD-1. Peresolimab potentially stimulates physiological immune inhibitory pathways to restore immune homeostasis.
M59182 Anzurstobart Anzurstobart (CC-95251; BMS-986351) is a high-affinity, fully human monoclonal anti-SIRPα antibody that blocks the binding of CD47 to SIRPα. Anzurstobart enhances macrophage phagocytic activity against DLBCL cell lines in co-culture models when combined with the antibody Rituximab.
M59172 PF-03732010 (CHO) PF-03732010 is a humanized antibody targeting CDH3/P-cadherin.
M59147 Ecromeximab Ecromeximab (KM 871; KW 2871) is an IgG-κ chimeric antibody targeting ganglioside GD3.
M59069 Depatuxizumab Depatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR.
M59065 Lifastuzumab Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody.
M58975 ADCT-901
M58698 Anti-Mouse CD40 Antibody (Clone FGK45) In vivo CD40 is a 48 kD type I transmembrane glycoprotein that is a member of the TNFR superfamily. CD40 interacts with TNFR2 and is involved in the regulation of signal transduction. CD40 is a potential target for cancer immunotherapy. CD40 is widely expressed on antigen-presenting cells such as dendritic cells, B cells, macrophages, and monocytes, in addition to non-immune endothelial cells, basal epithelial cells, and a variety of tumors. Clone FGK45 recognizes an epitope on mouse CD40.
M58555 Volociximab Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs).
M58432 Anti-Mouse RANKL/CD254 Antibody (Clone 7C6) In vivo Anti-Mouse RANKL/CD254 Antibody (Clone 7C6) is a Mouse-derived VHH-mFc type antibody, targeting to mouse RANKL/CD254.
M58370 Gemtuzumab Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for the synthesis of antibody-drug conjugate (ADC) Gemtuzumab ozogamicin.
M55700 Anti-human CD52 mAb (HEK293)
M55669 Anti-Mouse IFNß (interferon beta) Antibody (Clone HDß-4A7) In vivo Anti-Mouse Interferon-beta (IFN-ß) (Clone HDß-4A7) recognizes an epitope on Mouse IFN-ß and binds specifically to murine IFNß and does not bind murine IFNg or several different IFNa species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms.
M55206 Lintuzumab Lintuzumab is a humanized monoclonal antibody directed against CD33, which is expressed on the majority of myeloblasts in acute myeloid leukemia.

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