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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M49470 MCLA-129 MCLA-129 is a 1+1 asymmetric c-Met/EGFR bispecific antibody that can be used in a variety of tumor-related studies.
M49469 CKD-702 CKD-702 is a c-Met/EGFR bispecific antibody that can be used in studies related to non-small cell lung cancer and gastric cancer.
M49455 CALY-002 CALY-002 is a potential best-in-class (BIC), humanized monoclonal antibody targeting IL-15 for studies related to immune diseases.
M49447 GS-1811 GS-1811 is a monoclonal antibody targeting CCR8 that selectively removes tumor-infiltrating T regulatory cells with immunosuppressive effects in the tumor microenvironment, and can be used in studies related to solid tumors.
M49444 BAY-3375968 BAY-3375968 is a monoclonal antibody targeting the CCR8 receptor that selectively reduces CCR8-positive Tregs through antibody-dependent cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP), and can be used in studies related to solid tumors.
M49442 BMS-986340 BMS-986340 is a human immunoglobulin G1 (IgG1) non-fucosylated (NF) monoclonal antibody to CCR8 that targets, binds to, and blocks CCR8 activity on CCR8-positive tumor-infiltrating regulatory T-cells (Tregs) in tumor microenvironments (TMEs) and prevents chemokine ligand (CCL1-CCR8)-mediated signaling.
M49436 V565 V565 is a novel antibody that specifically targets TNFα and can be used in studies related to Crohn's disease (CD).
M49354 Auremolimab Auremolimab is an ultra-humanized monoclonal antibody against IL-2Rβ (CD122) that targets and depletes tissue-resident memory T-cells, and may be used in vitiligo-related studies.
M45367 Genakumab Genakumab is a monoclonal antibody targeting IL-1β that can be used in studies related to gout.
M45250 DCSZ11 DCSZ11 is a monoclonal antibody targeting CD93 for studies related to solid tumors.
M45224 BI-1910 BI-1910 is a monoclonal antibody targeting anti-tumor necrosis factor receptor 2 (TNFR2).
M45223 Casdozokitug Casdozokitug is an IgG1κ antibody targeting IL27.
M45222 TEV’574 TEV'574 is a TL1A antibody with a unique binding epitope that blocks TL1A binding to the DR3 receptor without affecting TL1A binding to the DcR3 pseudoreceptor. It can be used in studies related to ulcerative colitis and Crohn's disease.
M45221 TEV-48574 TEV-48574 is a TL1A-targeted monoclonal antibody that can be used in studies related to ulcerative colitis (UC).
M45160 LY3499446 LY3499446 is a KRAS G12C covalent inhibitor for studies related to non-small cell lung cancer (NSCLC).
M45134 IMVT-1402 IMVT-1402 is a potential best-in-class (BIC) neonatal Fc receptor (FcRn)-targeting antibody for studies related to autoimmune diseases.
M45115 PMN310 PMN310 is a beta-amyloid oligomer (AβO) antibody that can be used in studies related to Alzheimer's disease (AD).
M43951 MK-2060 MK-2060 is a monoclonal antibody with dual activity to inhibit coagulation factors XI and Xia, blocking both the activation of coagulation factor XI and the downstream activity of the activated protein. It can be used in studies related to end-stage renal disease (ESRD).
M43950 Xisomab 3G3 Xisomab 3G3 is a recombinant human-derived monoclonal antibody to coagulation factor XI (F11) that blocks factor XI activation mediated by factor XIIa in a concentration-dependent manner.
M43942 AMG-820 AMG-820 is an anti-colony stimulating factor 1 receptor (CSF1R) monoclonal antibody.

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